Sloane received a number of honours related to his practice of medicine. By 1705, the Edinburgh College of Physicians elected him as a fellow and from 1719 to 1735, he was the President of the Royal College of Physicians in London. In 1712, Sloane became Physician Extraordinary to the Queen, even attending her during her last illness in 1714, and was frequently called in to treat members of the royal family. George I named Sloane a Baronet in 1716, while George II made him Physician-in-Ordinary.